Buy promethazine hydrochloride And Codeine Online
Price range: £210.00 through £650.00
| 1 bottles | £210.00 | |
| 2 bottles | £380.00 | |
| 4 bottles | £650.00 |
Promethazine Hydrochloride: Comprehensive Guide
Promethazine hydrochloride is an antihistamine that works by blocking the effects of histamine, a natural chemical in the body responsible for allergy symptoms such as itching, swelling, and runny nose. Additionally, it exhibits sedative and antiemetic (anti-nausea) properties, making it useful for conditions beyond allergies.
Promethazine Hydrochloride: Comprehensive Guide and Uses in the UK & Europe
Promethazine hydrochloride is a versatile first-generation antihistamine widely used in the UK and Europe for managing a variety of allergic conditions, nausea, motion sickness, sedation, and related symptoms. Available in tablets, syrup, and injectable forms, promethazine hydrochloride offers effective relief for allergies, vomiting, and sleep disturbances, making it a common medication in both outpatient and hospital settings.
What is Promethazine Hydrochloride?
Promethazine hydrochloride is an antihistamine that works by blocking the effects of histamine, a natural chemical in the body responsible for allergy symptoms such as itching, swelling, and runny nose. Additionally, it exhibits sedative and antiemetic (anti-nausea) properties, making it useful for conditions beyond allergies.
Uses and Indications of Promethazine Hydrochloride
Promethazine hydrochloride is prescribed for multiple medical uses including:
| Indication | Description | Common Dosage Forms |
|---|---|---|
| Allergies and Hay Fever | Relief from symptoms like sneezing, itching, watering eyes, and hives (urticaria) | Tablets, Syrup |
| Motion Sickness and Vertigo | Prevention and treatment of nausea, vomiting, dizziness due to travel or inner ear problems | Tablets, Syrup, Suppositories |
| Nausea and Vomiting | Control of post-operative, chemotherapy-induced, or pregnancy-related nausea | Tablets, Syrup |
| Sedation and Sleep Disorders | Short-term treatment of insomnia and to calm agitation, especially in hospital settings | Tablets, Injectable Forms |
| Anaphylaxis Adjunct Therapy | Used alongside epinephrine during severe allergic reactions (anaphylaxis) | Tablets |
| Common Cold and Cough Relief | Combined with other drugs to alleviate cough and cold symptoms | Syrup combinations |
Why Choose Promethazine Hydrochloride?
-
Proven Track Record: Promethazine is preferred in the UK for nausea during pregnancy (hyperemesis gravidarum) due to its long history and well-studied safety profile.
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Multi-Symptom Relief: Not only treats allergies but also prevents nausea and calms anxiety.
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Various Forms and Dosages: Available as oral tablets, syrup, suppositories, and injections, allowing flexible treatment options.
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Accessibility: Available on prescription and over the counter in some formulations under brand names like Phenergan, Sominex, Fedril, and Night Nurse.
Detailed Dosage Recommendations (UK Guidelines)
| Condition | Adult Dose | Children Dose | Notes |
|---|---|---|---|
| Allergies and Hay Fever | 10-25 mg once daily or at bedtime | 6.25-12.5 mg 2-3 times daily | Adjust to minimal effective dose |
| Motion Sickness | 25 mg 30-60 minutes before travel | 12.5-25 mg 1-2 times daily | May repeat dose every 8-12 hours if needed |
| Nausea and Vomiting | 25 mg every 4-6 hours as needed | 0.5 mg per pound body weight | Max dose not to exceed recommended limits |
| Sedation and Agitation | 25 mg prior to surgery or bedtime | Use with caution; consult specialist | Usually short-term use |
Note: Dosage should always be individualized based on patient condition, age, weight, and response.
Side Effects and Safety Information
While effective, promethazine hydrochloride may cause side effects that require attention and caution:
| Common Side Effects | Description |
|---|---|
| Drowsiness and Dizziness | Sedative effect can impair alertness |
| Dry Mouth | Common anticholinergic effect |
| Blurred Vision | Rare, usually transient |
| Confusion or Restlessness | More common in elderly or high doses |
| Allergic Reactions | Rash, swelling, difficulty breathing may occur |
Important Safety Precautions:
-
Avoid alcohol and CNS depressants during treatment.
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Not recommended for children under 2 years.
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Avoid driving or operating machinery if drowsiness occurs.
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Use caution in elderly patients due to increased risk of cognitive impairment and falls.
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Consult a healthcare professional before use during pregnancy and breastfeeding.
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Inform the prescriber of all current medications to avoid drug interactions, especially with opioids, sedatives, or MAO inhibitors.
Promethazine Hydrochloride in the UK Market
Popular brand names containing promethazine hydrochloride in the UK include:
| Brand Name | Common Usage | Available Forms |
|---|---|---|
| Phenergan | Allergy relief, nausea, sedation | Tablets, Syrup, Suppositories |
| Sominex | Short-term insomnia relief | Tablets |
| Fedril | Combined cold and allergy relief | Syrup with other active ingredients |
| Night Nurse | Multi-symptom cold and flu relief | Syrup combination with analgesics |
Frequently Asked Questions (FAQs)
1. Can promethazine hydrochloride be bought without a prescription in the UK?
Some low-dose formulations like Sominex (for sleep) are available over the counter, while others require a prescription.
2. How long does promethazine take to work?
Promethazine usually starts working within 20-30 minutes after oral administration, with effects lasting several hours.
3. Is promethazine safe during pregnancy?
It is often considered the first choice for nausea in pregnancy but should only be used under medical supervision.
4. Can I drive after taking promethazine?
Driving is not recommended if you experience drowsiness, dizziness, or blurred vision.
Conclusion
Promethazine hydrochloride is a clinically proven, multi-functional antihistamine extensively used across the UK and Europe. Its rich history combined with flexible dosing and broad therapeutic coverage makes it a trusted solution for allergy relief, motion sickness, sedation, and nausea. Whether prescribed in combination cough syrups or standalone antihistamine tablets, promethazine hydrochloride continues to be a mainstay medication for managing common and complex symptoms safely and effectively.
For purchase, advice, and more detailed guidance, visit Nearby Pharmacy UK for prompt availability and expert consultation.
| Quantity | 1 bottles, 2 bottles, 4 bottles |
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